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Release date:2022/9/13 11:10:56

PROTAC-linker

Biopharma PEG provides high-purity PROTAC PEG linkers with various active groups to assist with your PROTAC-related projects. PEG linkers are the most common motifs incorporated into PROTAC linker structures. 

  • ▶ PEG linker increases the PROTAC water solubility, affecting the cell permeability, thereby improving oral absorption
  • ▶ PEG linker can easily tune their length and composition via some chemical methods. Linker length contributes to degradation efficiency.
  • ​▶ Bi-functionalized PEG motifs enable the rapid and facile assembly of potent degrader structures.

PROTAC PEG Linkers

NH2-PEG2-COOH, CAS No. 791028-27-8
NH2-PEG3-COOH, CAS NO. 784105-33-5
NH2-PEG4-COOH, CAS NO. 663921-15-1
NH2-PEG-COOH
NH2-PEG2-CH2COOH, CAS NO. 134978-97-5
NH2-PEG3-CH2COOH, CAS NO. 134978-99-7
NH2-PEG4-CH2COOH, CAS NO. 195071-49-9
NH2-PEG-CH2COOH
N3-PEG3-OH, CAS NO. 86520-52-7
N3-PEG4-NH2, CAS NO.  951671-92-4
N3-PEG4-COOH, CAS NO. 1257063-35-6
N3-PEG
Fmoc-NH-PEG3-COOH
CAS NO. 867062-95-1
Boc-NH-PEG4-OH
CAS NO. 106984-09-2
Tos-PEG4-Tos
CAS No. 37860-51-8
Fmoc-NH-PEG3-COOH Boc-NH-PEG4-OH Tos-PEG4-Tos
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