• CAS No.：
  663921-15-1
• Synonyms：
  Amine-PEG4-COOH；α-amine-ω-propionic acid tetraethylene glycol
  3-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]propionicacid
  1-Amino-3,6,9,12-tetraoxapentadecan-15-oicacid
  Amino-PEG4-acid
  H2N-PEG4-CH2CH2COOH
  Amino-dPEG4-acid
  1-Amino-3,6,9,12-tetraoxa-15-pentadecanoic acid
  
• Purity：
  ≥95%
• MF：
  C₁₁H₂₃NO₆
• MW：
  265.3
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

NH2-PEG4-COOH (Amino-PEG4-propionic acid) is a PEG linker that can be used as drug carrier, ADC linker and PROTAC linker. It has been shown to have a high uptake in cancer cells and tumor vasculature. It creates conjugates with drugs or radiotracers to facilitate their delivery into the tumor. This polymer can be synthesized on a solid phase and conjugated to cytotoxic drugs or radiotracers via the amino group of its side chain. Amino-PEG4-propionic acid has also been shown to have low expression in normal cells, which makes it an effective carrier for drugs that are toxic to normal cells.
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