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Drug Delivery

Drug delivery describes the tactic and approach to delivering medicine or prescription drugs and alternative xenobiotics to their website of action among an organism, with the goal of achieving a therapeutic outcome. problems with pharmacodynamics and pharmacology square measure necessary concerns for drug delivery.

The PEGylated drug delivery system is a cutting-edge application of PEG derivatives in the pharmaceutical field. The PEGylation technology can also be used in delivery systems for drugs such as siRNA, mRNA, pDNA, etc. Among many drug delivery systems, PEGylated LNP(Lipid Nanoparticle)drug delivery system is widely used for the mRNA and siRNA drug delivery. For example, PEGylated LNPs are used in Pfizer/BioNTech and Moderna's COVID-19 mRNA vaccines. 

Biopharma PEG provides PEG linkers from lab to GMP commercial scale for your drug delivery. Contact us at sales@biochempeg.com if you are interested in our PEG products. 

References:
​1. Suk JS, Xu Q, Kim N, Hanes J, Ensign LM. PEGylation as a strategy for improving nanoparticle-based drug and gene delivery. Adv Drug Deliv Rev. 2016;99(Pt A):28-51. doi:10.1016/j.addr.2015.09.012

Catalog No. Name Structure M.W. Purity
MF001002 mPEG-OH mPEG-OH ≥95%
MF001050 mPEG-NH2.HCl mPEG-NH2.HCl ≥95%
MF001017 mPEG-COOH mPEG-COOH ≥95%
MF001003 mPEG-SH mPEG-SH ≥95%
MF001096 mPEG-DSPE mPEG-DSPE ≥95%
MF001317 mPEG-DMG mPEG-DMG ≥95%
MF001318 mPEG-N,N-Ditetradecylacetamide (ALC-0159) mPEG-N,N-Ditetradecylacetamide (ALC-0159) ≥95%
MF001098 mPEG-DPPE mPEG-DPPE ≥95%
MF001121 mPEG-AA (mPEG-CM) mPEG-AA (mPEG-CM) ≥95%
MF001022 mPEG-Mal mPEG-Mal ≥95%
MF001170 mPEG-CH2CH2CH2-NH2 mPEG-CH2CH2CH2-NH2 ≥95%
MF001163 mPEG-PLGA(75:25)(5K) mPEG-PLGA(75:25)(5K) ≥95%