NH2-PEG2-CH2COOH
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MSDS
NH2-PEG2-CH2COOH

CatalogID: 10803 Purity: ≥95% CAS NO.: 134978-97-5

  • CAS No.:
    134978-97-5
  • Synonyms:
    Amine-PEG2-CH2COOH
    2-(2-(2-Aminoethoxy)ethoxy)acetic acid
    8-Amino-3,6-dioxaoctanoic acid
  • Purity:
    ≥95%
  • MF:
    C6H13NO4
  • MW:
    163.2
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:
    Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

NH2-PEG2-CH2COOH is a PEG compound containing an amino group with a terminal carboxylic acid. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

NH2-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. It is also a semaglutide intermediate. Other semaglutide intermediates include Boc-NH-PEG2-CH2COOHFmoc-NH-PEG2-CH2COOH and CH2COOH-PEG2-NH2.HCl.