• CAS No.：
  951671-92-4
• Synonyms：
  Azido-PEG4-Amine
  Azido-PEG4-NH2
  O-(2-Aminoethyl)-O'-(2-azidoethyl)triethyleneGlycol
  14-Azido-3,6,9,12-tetraoxatetradecan-1-amine
  14-AZIDO-3,6,9,12-TETRAOXATETRADECAN-1-YLAMINE
  2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethanamine
  
• Purity：
  ≥95%
• MF：
  C₁₀H₂₂N₄O₄
• MW：
  262.31
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

N3-PEG4-NH2 (Azide-PEG4-Amine) is a very monodispersed bifunctional crosslinker. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media.

It can be also called PROTAC Linker 20, a PEG-based PROTAC linker that can be used in the synthesis of a series of PROTACs. And also. it can be used as ADC linker. 

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