Alkyne-PEG4-NH2
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MSDS
Alkyne-PEG4-NH2

CatalogID: 10749 Purity: ≥95% CAS NO.: 1013921-36-2

  • CAS No.:
    1013921-36-2
  • Synonyms:
    Propargyl-PEG4-NH2
    H2N-PEG4-Propyne
    Amino-PEG4-alkyne
    Alkyne-PEG4-Amine
    Propargyl-PEG4-Amine
    Propyne-PEG4-Amine
    Triethylene glycol 2-aminoethyl propargyl ether
    1-Amino-3,6,9,12-tetraoxapentadec-14-yne
    3,6,9,12-tetraoxapentadec-14-yn-1-amine
  • Purity:
    ≥95%
  • MF:
    C11H21NO4
  • MW:
    231.3
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:
    Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Alkyne-PEG4-NH2, also known as Alkyne-PEG4-amine, is a PEG derivative with an alkyne functional group (-C≡C) and an amino group (-NH2). The alkyne group enables selective conjugation reactions via copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC) reactions, commonly known as click chemistry. These reactions facilitate the attachment of Alkyne-PEG4-NH2 to molecules, surfaces, or nanoparticles bearing azide groups, allowing for precise control over bioconjugation reactions. ​

The amino group provides versatility for further chemical modification. It can react with activated carboxylic acid groups or other reactive functional groups to form stable amide bonds or other types of linkages, enabling the attachment of Alkyne-PEG4-NH2 to a wide range of molecules or surfaces. ​

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