• Synonyms：
  Biotin-PEG-Maleimide
  
• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Biotin-PEG-Mal (Biotin-PEG-Maleimide) is a bifunctional PEG reagent with a biotin group at one end and a maleimide group at the other. The biotin group serves as an affinity label for proteins such as avidin and streptavidin, enabling targeted binding with high specificity and affinity. The maleimide group reacts with thiol groups on cysteine residues or other thiol-containing molecules through Michael addition, forming stable thioether bonds. This reagent is commonly used in bioconjugation, protein labeling, and the development of targeted drug delivery systems due to its versatile functional groups and enhanced solubility provided by the PEG spacer.

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Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. Sumiyoshi, R., Yamagishi, M., & Yajima, J. (2025). In vitro motility-based tether-scanning of the kinesin motor domain. MethodsX, 15, 103719. https://doi.org/10.1016/j.mex.2025.103719​

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