• CAS No.：
  2395004-21-2
• Synonyms：
  BocNH-PEG11-CH2CH2N3
  N3-PEG11-NH-Boc
  
• Purity：
  ≥89%
• MF：
  C₂₉H₅₈N₄O₁₃
• MW：
  670.79
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

t-Boc-N-Amido-PEG11-Azide (Boc-NH-PEG11-N3) includes both an azide group and a Boc-protected amino group. The PEG spacer boosts the compound's solubility in water. The azide group can participate in Click Chemistry reactions with alkyne, BCN, or DBCO, forming a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form a free amine, which can undergo amide coupling with carboxylic acid bearing biomolecules.

Boc-NH-PEG11-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Large-scale PEGs and GMP-grade PEGs are made-to-order. Please contact us at sales@biochempeg.com for more details. 

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562