Boc-NH-PEG12-COOH
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Boc-NH-PEG12-COOH

CatalogID: 11611 Purity: ≥95% CAS NO.: 1415981-79-1

  • CAS No.:
    1415981-79-1
  • Synonyms:
    t-Boc-NH-amido-PEG12-COOH
  • Purity:
    ≥95%
  • MF:
    C32H63NO16
  • MW:
    717.8411
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:
    Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Boc-NH-PEG12-COOH, also referred to as t-Boc-N-Amido-PEG12-acid, is a PEG derivative consisting of a Boc-protected amine group (NH) at one end and a carboxylic acid group (COOH) at the other end.  The terminal carboxylic acid readily reacts with primary and secondary amine under EDC, DCC, HATU or other amide coupling conditions to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine, which can undergo amide coupling with carboxylic acid bearing biomolecules.

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