Boc-NH-PEG3-Tos
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MSDS
Boc-NH-PEG3-Tos

CatalogID: 12436 Purity: ≥95% CAS NO.: 1246999-33-6

  • CAS No.:
    1246999-33-6
  • Synonyms:
    Boc-NH-PEG3-Tosylate
    2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl 4-methylbenzenesulfonate
    5,8,11-Trioxa-2-azatridecanoic acid, 13-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
  • Purity:
    ≥95%
  • MF:
    C20H33NO8S
  • MW:
    447.54
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:

t-Boc-N-Amido-PEG3-Tos (CAS No. 1246999-33-6) is a monodisperse PEG linker, which can act as PROTAC linkers. PROTACs contain two different ligands linked by a linker; one for the E3 ubiquitin ligase and the other for the target protein. PROTACs use the intracellular ubiquitin-proteasome system to selectively degrade the target protein.

Biopharma PEG offers a wide range of PEG products from lab to commercial scale in both non-GMP and GMP grades. Email at sales@biochempeg.com and start using a superior product for your next product R&D project.

References:
​An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.