• CAS No.：
  1246999-33-6
• Synonyms：
  Boc-NH-PEG3-Tosylate
  2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl 4-methylbenzenesulfonate
  5,8,11-Trioxa-2-azatridecanoic acid, 13-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
  
• Purity：
  ≥95%
• MF：
  C₂₀H₃₃NO₈S
• MW：
  447.54
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  

t-Boc-N-Amido-PEG3-Tos (CAS No. 1246999-33-6) is a monodisperse PEG linker, which can act as PROTAC linkers. PROTACs contain two different ligands linked by a linker; one for the E3 ubiquitin ligase and the other for the target protein. PROTACs use the intracellular ubiquitin-proteasome system to selectively degrade the target protein.

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References:
​An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.