• CAS No.：
  127457-79-8
• Synonyms：
  HOOCCH2CH2-PEG3-NH2.HCl
  3-(2-(2-Aminothoxy)ethoxy)propanoic acid HCl
  
• Purity：
  ≥95%
• MF：
  C₉H₂₀NO₅Cl
• MW：
  257.7
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

COOH-PEG3-NH2.HCl, also known as Amine-PEG3-carboxylic acid (CAS: 127457-79-8), is a bifunctional PEG derivative featuring both a terminal carboxyl and amino group linked by a PEG3 spacer. This hydrophilic spacer enhances solubility in water, making it well-suited for bioconjugation applications. The terminal amino group can participate in reactions with activated esters or carbonyl compounds, enabling versatile coupling strategies such as reductive amination. Meanwhile, the carboxyl group can form stable amide bonds with primary amines in the presence of carbodiimide activators (e.g., EDC or HATU), broadening its utility in biomolecule modification and pharmaceutical synthesis.

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