• CAS No.：
  1415800-35-9
• Synonyms：
  Mal-NH-PEG4-CH2CH2COOtBu
  Mal-Amido-PEG4-t-butyl ester
  Mal-amido-PEG4-Boc
  Maleimide-C2-amido-PEG4-Carboxylic acid tert-butyl ester
  
• Purity：
  ≥95%
• MF：
  C₂₂H₃₆N₂O₉
• MW：
  472.5
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Mal-NH-PEG4-OtBu, also known as Mal-Amido-PEG4-t-butyl ester, is a PEG linker terminated with a maleimide group and a t-butyl ester group.

The hydrophilic PEG spacer enhances the solubility of Mal-NH-PEG4-OtBu in aqueous media, facilitating its use in biological and biomedical applications. The t-butyl protected carboxyl group provides stability and protection during synthesis and handling and can be selectively deprotected under acidic conditions, exposing the carboxyl group to further conjugation reactions.

The maleimide group serves as a reactive site for the formation of covalent bonds with thiol groups present in biomolecules or surfaces. This enables the conjugation of Mal-NH-PEG4-OtBu to thiol-containing molecules, facilitating the attachment of biomolecules or ligands to surfaces or carriers.

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