• Synonyms：
  Amino-PEG-RGD
  Amine-PEG-ARG-GLY-ASP
  
• Purity：
  ≥90%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

NH2-PEG-RGD is a PEG linker terminated with an amine group (NH2) and RGD peptide motif. RGD (arginine-glycine-aspartic acid) is a well-known cell adhesion motif found in extracellular matrix proteins like fibronectin and vitronectin. It interacts with cell surface integrin receptors, particularly αvβ3 and α5β1 integrins, to mediate cell adhesion, migration, and signaling processes.

NH2-PEG-RGD is commonly used in biomaterials and tissue engineering applications to functionalize surfaces or nanoparticles, allowing for enhanced cell attachment and targeting of specific cell types. By conjugating the RGD motif to the PEG spacer, NH2-PEG-RGD provides a flexible and biocompatible platform for the design of biomaterials with improved cell interactions and tissue integration properties. It finds applications in areas such as regenerative medicine, drug delivery, and targeted cancer therapy, offering researchers a powerful tool to modulate cell-material interactions for various biomedical applications.

Biopharma PEG offers a wide range of PEG products from lab to commercial scale in both non-GMP and GMP grades. Email at [email protected] and start using a superior product for your next product R&D project.

Cited Publications

Our NH2-PEG-RGD has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. Magnetite Nanodiscs Activate Mechanotransductive Calcium Signaling in Diverse Cell Types, Jacob L. Beckham, Ye Ji Kim, Emmanuel Vargas Paniagua, Noah Kent, Keisuke Nagao, Sharmelee Selvaraji, Florian Koehler, Elian Malkin, Xavier Smith, Anthony Tabet, Sehoon Kang, and Polina Anikeeva, Journal of the American Chemical Society 2025 147 (16), 13303-13314, DOI: 10.1021/jacs.4c18227​

View more publications citing Biopharma PEG products.