• CAS No.：
  1446282-18-3
• Synonyms：
  Amino-PEG5-t-butyl ester
  tert-Butyl 1-amino-3,6,9,12,15-pentaoxaoctadecan-18-oate
  Amino-PEG5-Boc
  
• Purity：
  ≥95%
• MF：
  C₁₇H₃₅NO₇
• MW：
  365.5
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Monodisperse Amino-PEG5-t-butyl ester (NH2-PEG5-CH2CH2COOtBu) is a heterobifunctional, PEGylated crosslinker features an amino (NH2) group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. It can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.

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