NHS-PEG-RGD
NHS-PEG-RGD

CatalogID: 11075 Purity: ≥95%

  • Synonyms:
    NHS-PEG-ARG-GLY-ASP
  • Purity:
    ≥95%
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:
    Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
The applications of RGD peptides includes inhibition of apoptosis, angiogenesis and tumor formation. RGD peptides are used as coating surfaces for biomaterials to enhance drug delivery and imaging for disease diagnosis. PEGylated RGD can be cross-linked with other molecules via reactive terminal groups on PEG for use in various biomedical studies.

References:
1. Eto Y, Gao J Q, Sekiguchi F, et al. PEGylated adenovirus vectors containing RGD peptides on the tip of PEG show high transduction efficiency and antibody evasion ability. The Journal of Gene Medicine, 2005, 7(5): 604-612.
2. Xiong Z, Cheng Z, Zhang X, et al. Imaging chemically modified adenovirus for targeting tumors expressing integrin αvβ3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene.Journal of nuclear medicine,2006, 47(1): 130-139.