1835705-72-0, Pomalidomide-PEG2-butyl iodide

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MSDS

Pomalidomide-PEG2-butyl iodide

≥95% CatalogID: 12465 Purity: ≥95% CAS NO.: 1835705-72-0

CAS No.：
1835705-72-0
Synonyms：
Pomalidomide-NH-CO-PEG2-butyl iodide
Pomalidomide-2-2-6-I
N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-2-(2-((6-iodohexyl)oxy)ethoxy)acetamide
Purity：
≥95%
MF：
C₂₃H₂₈In₃O₇
MW：
585.39
Recommended Storage Condition：
Store at -5°C,keep in dry and avoid sunlight.
Uses：
Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Pomalidomide-PEG2-butyl iodide (CAS No.1835705-72-0) is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal iodoalkane that reacts with the nucleophilic group of the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation.