Pomalidomide-PEG2-butyl iodide
Pomalidomide-PEG2-butyl iodide

CatalogID: 12465 Purity: ≥95% CAS NO.: 1835705-72-0

  • CAS No.:
    1835705-72-0
  • Synonyms:
    Pomalidomide-NH-CO-PEG2-butyl iodide
    Pomalidomide-2-2-6-I
    N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-2-(2-((6-iodohexyl)oxy)ethoxy)acetamide
  • Purity:
    ≥95%
  • MF:
    C23H28In3O7
  • MW:
    585.39
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:
    Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
Pomalidomide-PEG2-butyl iodide (CAS No.1835705-72-0)  is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal iodoalkane that reacts with the nucleophilic group of the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation.