• Synonyms：
  SH-PEG-NHS
  Thiol-PEG-NHS
  
• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-SC (SH-PEG-NHS) is a linear heterobifunctional PEG reagent with a Thiol and a NHS ester group.  NHS ester group can react with primary amine, Thiol(SH) group can react with maleimide and transition metal surface including gold (Gold nanoparticles-SH-PEG-NHS).

Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. Agu, C.V., Cook, R.L., Martelly, W. et al. Multiplexed proteomic biosensor platform for label-free real-time simultaneous kinetic screening of thousands of protein interactions. Commun Biol 8, 468 (2025). https://doi.org/10.1038/s42003-025-07844-z 
2. Novel sensor-integrated proteome on chip (SPOC) platform with thousands of folded proteins on a 1.5 sq-cm biosensor chip to enable high-throughput real-time label-free screening for kinetic analysis, Chidozie Victor Agu, Rebecca L Cook, William Martelly, Lydia R Gushgari, Mukilan Mohan, Bharath Takulapalli, bioRxiv 2024.01.23.575909; doi: https://doi.org/10.1101/2024.01.23.575909 
3. A Three-Dimensional Printable Hydrogel Formulation for the Local Delivery of Therapeutic Nanoparticles to Cervical Cancer, Mariia Kiseleva, Mahmoud M. Omar, Élodie Boisselier, Svetlana V. Selivanova, and Marc-André Fortin, ACS Biomaterials Science & Engineering 2022 8 (3), 1200-1214, DOI: 10.1021/acsbiomaterials.1c01399 
4. Putra, Amal Rezka and Yulizar, Yoki and Ritawidya, Rien and Apriandanu, Dewangga Oky Bagus and Juliyanto, Sumandi and Fikri, Ahsanal and Surya, Rizki Marcony, Nimotuzumab Iodine-131 Conjugated with Mnfe2o4 for Potential Dual-Modality (Mri/Spect) Imaging Nanoprobe. Available at SSRN: https://ssrn.com/abstract=4017231 or http://dx.doi.org/10.2139/ssrn.4017231 
5. Mills, S. C., Starr, N. E., Bohannon, N. J., & Andrew, J. S. (2021). Chelating Agent Functionalized Substrates for the Formation of Thick Films via Electrophoretic Deposition. Frontiers in Chemistry, 9, 703528. https://doi.org/10.3389/fchem.2021.703528

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