• Synonyms：
  SH-PEG-NHS
  Thiol-PEG-NHS
  
• Purity：
  ≥90%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-SC (SH-PEG-NHS) is a linear heterobifunctional PEG reagent with a Thiol and a NHS ester group.  NHS ester group can react with primary amine, Thiol(SH) group can react with maleimide and transition metal surface including gold (Gold nanoparticles-SH-PEG-NHS).

Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. Kiliç, A. (2026). Polyethylene glycol passivated nanoplasmonic biosensor for sensitive detection in complex biological samples. Gümüşhane Üniversitesi Fen Bilimleri Dergisi, 16(1), 325-338. https://doi.org/10.17714/gumusfenbil.1821435
2. Agu, C.V., Cook, R.L., Martelly, W. et al. Multiplexed proteomic biosensor platform for label-free real-time simultaneous kinetic screening of thousands of protein interactions. Commun Biol 8, 468 (2025). https://doi.org/10.1038/s42003-025-07844-z 
3. Novel sensor-integrated proteome on chip (SPOC) platform with thousands of folded proteins on a 1.5 sq-cm biosensor chip to enable high-throughput real-time label-free screening for kinetic analysis, Chidozie Victor Agu, Rebecca L Cook, William Martelly, Lydia R Gushgari, Mukilan Mohan, Bharath Takulapalli, bioRxiv 2024.01.23.575909; doi: https://doi.org/10.1101/2024.01.23.575909 
4. A Three-Dimensional Printable Hydrogel Formulation for the Local Delivery of Therapeutic Nanoparticles to Cervical Cancer, Mariia Kiseleva, Mahmoud M. Omar, Élodie Boisselier, Svetlana V. Selivanova, and Marc-André Fortin, ACS Biomaterials Science & Engineering 2022 8 (3), 1200-1214, DOI: 10.1021/acsbiomaterials.1c01399 
5. Putra, Amal Rezka and Yulizar, Yoki and Ritawidya, Rien and Apriandanu, Dewangga Oky Bagus and Juliyanto, Sumandi and Fikri, Ahsanal and Surya, Rizki Marcony, Nimotuzumab Iodine-131 Conjugated with Mnfe2o4 for Potential Dual-Modality (Mri/Spect) Imaging Nanoprobe. Available at SSRN: https://ssrn.com/abstract=4017231 or http://dx.doi.org/10.2139/ssrn.4017231 
6. Mills, S. C., Starr, N. E., Bohannon, N. J., & Andrew, J. S. (2021). Chelating Agent Functionalized Substrates for the Formation of Thick Films via Electrophoretic Deposition. Frontiers in Chemistry, 9, 703528. https://doi.org/10.3389/fchem.2021.703528

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