mPEG36-NH2
mPEG36-NH2

CatalogID: 11871 Purity: ≥95% CAS NO.: 32130-27-1

  • CAS No.:
    32130-27-1
  • Synonyms:
    mPEG36-Amine
  • Purity:
    ≥95%
  • MF:
    C73H149NO36
  • MW:
    1616.95
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:

mPEG36-Amine is a linear methoxy PEG reagent with reactive amine (NH2) group that react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds. Amines can also react with carbonyl groups, such as ketones and aldehydes.

mPEG36-NH2 is potentially useful in numerous applications. Such applications include the following:

  1. Act as a linker for Antibody-Drug Conjugates (ADCs), improving the drug's solubility and stability;
  2. Passivates nanoparticle surfaces, including those of carbon nanotubes and graphene oxide;
  3. Creates a non-immune "stealth" coating for liposomes and micelles;
  4. Increase the hydrodynamic volume of small molecules, including peptides and antibody fragments;
  5. Increases the water solubility of hydrophobic molecules.

Biopharma PEG, as a leading PEG linker supplier, provides mPEG36-NH2 from lab to GMP commercial scale for your need. Email at sales@biochempeg.com and start using a superior product for your next product R&D project.

References:
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.