2-((Azido-PEG8-carbamoyl)methoxy)acetic acid
2-((Azido-PEG8-carbamoyl)methoxy)acetic acid

CatalogID: 12277 Purity: ≥95% CAS NO.: 846549-37-9

  • CAS No.:
  • Synonyms:
  • Purity:
  • MF:
  • MW:
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:
    Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
2-((Azido-PEG8-carbamoyl)methoxy)acetic acid (CAS NO.: 846549-37-9)  is a PEG linker containing an azide group with a terminal carboxylic acid. It is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

2-((Azido-PEG8-carbamoyl)methoxy)acetic acid can act as
linker for Antibody-Drug Conjugates (ADCs). It is an intermediate of ADC drug Sacituzumab Govitecan (IMMU-132) which was approved by FDA on April 22, 2020. It was used to treat adults triple-negative breast cancer.