• Synonyms：
  AlKyne-PEG-Thiol
  
• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Alkyne-PEG-SH is a linear, heterobifunctional  PEG linker featuring an alkyne group at one end and a thiol (–SH) group at the other. This unique structure enables efficient bioconjugation and surface modification through click chemistry (alkyne-azide cycloaddition) and thiol-based reactions with maleimide or metal surfaces.

Biopharma PEG offers a wide range of PEG linkers on both lab and commercial scales. Email at sales@biochempeg.com and start using a superior product for your next product R&D project.

Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. ​Raîche-Marcoux Gabrielle , Méthot Sébastien , Tchatchouang Ange , Bettoli Camille , Maranda Cloé , Loiseau Alexis , Proulx Stéphanie , Rochette Patrick J. , Genin Emilie , Boisselier Élodie, Localization of fluorescent gold nanoparticles throughout the eye after topical administration, Frontiers in Medicine, Volume 12 - 2025, DOI:10.3389/fmed.2025.1557611 
2. Wiegand, T., Fratini, M., Frey, F., Yserentant, K., Liu, Y., Weber, E., Galior, K., Ohmes, J., Braun, F., Herten, D., Boulant, S., Schwarz, U. S., Salaita, K., Ada, E., & Spatz, J. P. (2020). Forces during cellular uptake of viruses and nanoparticles at the ventral side. Nature Communications, 11(1), 1-13. https://doi.org/10.1038/s41467-019-13877-w

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