• CAS No.：
  1426827-79-3
• Purity：
  ≥95%
• MF：
  C₁₅H₁₇NO₅
• MW：
  291.3
• Recommended Storage Condition：
  
• Uses：
  

Applications in Copper-Free Click Chemistry (SPAAC) & Amine Bioconjugation

BCN-Osu (endo-BCN-NHS carbonate, CAS 1426827-79-3) is a versatile, amine-reactive cyclooctyne crosslinking reagent. Combining a strain-promoted BCN group with an active N-hydroxysuccinimide (NHS) carbonate, it enables the seamless introduction of a BCN handle onto primary amine-containing molecules, peptides, proteins, or antibodies. The BCN group reacts rapidly and specifically with azide-tagged (-N3) biomolecules via Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC) under physiological conditions. This eliminates the need for cytotoxic copper catalysts, making it the ideal reagent for live-cell labeling, in vivo imaging, and biocompatible material functionalization.

Premium Click Chemistry Reagent: 
BCN-Osu (endo-BCN-NHS carbonate, CAS NO.: 1426827-79-3) is supplied at high purity (≥95%). Ideal for copper-free bioorthogonal labeling in live cells, proteins, and nanomedicines.

Related Products & Categories

• ● Category: BCN PEGs & Click Reagents | Click Chemistry Reagents
• ● BCN Derivatives: endo-BCN-PEG2-OH | endo-BCN-PEG3-Boc-amine | BCN-endo-PEG4-SPA
• ● Azide Click Partners: N3-PEG6-OH | N3-PEG11-NH2 | N3-PEG3-SPA
• ● Alternative Click Chemitsry PEGs: Azide(N3) PEGs | DBCO PEG | Alkyne PEG