• CAS No.：
  1347760-82-0
• Synonyms：
  Propargyl-PEG3-COOH
  
• Purity：
  ≥95%
• MF：
  C₁₀H₁₆O₅
• MW：
  216.2
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Alkyne-PEG3-COOH (Propargyl-PEG3-acid) is a functional PEG linker featuring a propargyl group and a terminal carboxylic acid. The carboxylic acid group enables amide bond formation with primary or secondary amines in the presence of coupling reagents like EDC or DCC, while the propargyl group reacts with azide-bearing molecules via copper-catalyzed azide-alkyne Click Chemistry, forming a stable triazole linkage.

This versatile, non-cleavable 3-unit PEG linker is widely used in the synthesis of antibody-drug conjugates (ADCs) and as a PEG-based PROTAC linker, supporting applications in targeted drug delivery and therapeutic development.

Biopharma PEG offers a wide range of PEG linkers on both lab and commercial scales. Email at sales@biochempeg.com and start using a superior product for your next product R&D project.