DBCO-PEG-NHS
Products
MSDS
DBCO-PEG-NHS

CatalogID: 10201 Purity: ≥95%

  • Synonyms:
    DBCO-PEG-SC
    Dibenzocycolctyne-PEG-NHS
  • Purity:
    ≥95%
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:
    Protein-peptide conjugates;• Antibody-enzyme or antibody-drug conjugates;• Protein or peptide-oligonucleotide conjugates;• Surface modification .

DBCO-PEG-NHS is a PEG derivative with a dibenzocyclooctyne (DBCO) functional group and an N-hydroxysuccinimide (NHS) ester moiety. The NHS ester group enables the selective coupling of the DBCO-PEG molecule to primary amines on biomolecules, such as proteins and peptides. The DBCO functional group further facilitates bioconjugation via copper-free click chemistry, specifically with molecules containing azide groups. This reaction, known as strain-promoted azide-alkyne cycloaddition (SPAAC), enables rapid, biocompatible, and specific conjugation under physiological conditions without the need for toxic catalysts. 

Biopharma PEG offers a wide range of PEG products from lab to commercial scale in both non-GMP and GMP grades. Email at sales@biochempeg.com and start using a superior product for your next product R&D project.