DSPE-PEG-RGD, Lipid PEG for Targeted Drug Delivery

DSPE-PEG-RGD

≥90% CatalogID: 11188 Purity: ≥90%

Synonyms：
DSPE-PEG-ARG-GLY-ASP
Purity：
≥90%
Recommended Storage Condition：
Store at -5°C,keep in dry and avoid sunlight.
Uses：
Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

DSPE-PEG-RGD is a PEGylated phospholipid derivative that contains the RGD peptide, a well-known targeting ligand for integrin receptors, and DSPE, a saturated 18 carbon phospholipid. DSPE-PEG-RGD can improve circulation behavior, enhance biocompatibility, and support active targeting in advanced drug delivery systems. It is especially useful in liposome, LNP, and nanomedicine development, where targeting efficiency is important.

In targeted delivery systems, passive accumulation alone is often not enough to achieve strong therapeutic performance. DSPE-PEG-RGD adds active targeting capability by using the RGD peptide to recognize integrin receptors on specific cells. This makes it a useful component in systems designed to improve uptake, selectivity, and therapeutic efficiency.

Cited Publications

Our DSPE-PEG-RGD has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

Kutlehria, S., Bagde, A., Patel, N., & Singh, M. (2019). Whole-Eye Perfusion Model for Screening of the Ocular Formulations via Confocal Laser Scanning Microscopy. AAPS PharmSciTech, 20(7), 307. https://doi.org/10.1208/s12249-019-1493-x

View more publications citing Biopharma PEG products.

Need Custom DSPE-PEG Conjugates or Specific Molecular Weights?

Biopharma PEG provides high-purity DSPE-PEG-RGD across a wide range of PEG molecular weights in both research scale and commercial GMP grade quantities. We also offer custom synthesis for specialized lipid anchors, precise linkers, and targeted ligand attachments tailored to your LNP and liposome drug delivery project.

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