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Polydispersed PEGs
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Multi-arm PEGs
- >Hydroxyl(OH) PEG
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- PEGs by Application
- Lipids for Lipid Nanoparticles (LNPs)
- PEG Raw Material
CatalogID: 12399 Purity: ≥95% CAS NO.: 1849616-42-7
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CAS No.:
1849616-42-7 -
Synonyms:
mPEG-DTA
Methoxypoly(ethylene glycol) ditetradecylacetamide
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Purity:
≥95% -
Recommended Storage Condition:
Store at -5°C,keep in dry and avoid sunlight. -
Uses:
Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
mPEG-N,N-Ditetradecylacetamide, also called ALC-0159, mPEG-DTA, is a PEG/lipid conjugate (i.e. PEGylated lipid). According to public information, mPEG-DTA (ALC-0159) is one of the excipients of Pfizer's COVID-19 mRNA vaccine.
Biopharma PEG offers a wide range of PEG products from lab to commercial scale in both non-GMP and GMP grades. Besides PEG lipids, we can also provide helper lipids, such as cholesterol (plant-derived), and DSPE for your LNP formulation development. Email at sales@biochempeg.com and start using a superior product for your next product R&D project.
References:
1. Schoenmaker, Linde; Witzigmann, Dominik; Kulkarni, Jayesh A.; Verbeke, Rein; Kersten, Gideon; Jiskoot, Wim; Crommelin, Daan J. A. (2021-05-15). "mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability". International Journal of Pharmaceutics. 601: 120586. doi:10.1016/j.ijpharm.2021.120586. ISSN 0378-5173.
2. "Public Assessment Report Authorisation for Temporary Supply COVID-19 mRNA Vaccine BNT162b2 (BNT162b2 RNA) concentrate for solution for injection" (PDF). Regulation 174. MHRA. 15 December 2020.