Fmoc-NH-PEG2-CH2COOH
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MSDS
Fmoc-NH-PEG2-CH2COOH

CatalogID: 10821 Purity: ≥95% CAS NO.: 166108-71-0

  • CAS No.:
    166108-71-0
  • Synonyms:
    2-[2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid
    Fmoc-AEEA
    FMOC-AEEAC-OH
    2-[2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]acetic acid
  • Purity:
    ≥95%
  • MF:
    C21H23NO6
  • MW:
    385.42
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:
    Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Fmoc-NH-PEG2-CH2COOH is a monodispersed PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

It is a semaglutide side chain. Other semaglutide side chains includes NH2-PEG2-CH2COOHBoc-NH-PEG2-CH2COOH and CH2COOH-PEG2-NH2.HCl.