• CAS No.：
  1214319-92-2
• Synonyms：
  Azide-PEG8-COOH
  
• Purity：
  ≥95%
• MF：
  C₁₉H₃₇N₃O₁₀
• MW：
  467.51
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Monodisperse Azido-PEG8-acid (N3-PEG8-COOH) is a aqueous soluble PEG linker containing an azide (N3) and a terminal carboxylic acid (COOH) group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

N3-PEG8-COOH is a non-cleavable ADC linker containing 8-unit PEG that can be used to synthesize antibody drug conjugates (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.

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