NH2-PEG3-OH
NH2-PEG3-OH

CatalogID: 10710 Purity: ≥95% CAS NO.: 6338-55-2

  • CAS No.:
    6338-55-2
  • Synonyms:
    2-(2-(2-Aminoethoxy)ethoxy)ethanol
    AMINOETHOXY ETHOXY ETHANOL
    2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL
    2-[2-(2-Hydroxyethoxy)ethoxy]ethylamine
    3,6,9-Trioxadecylamine
    Triethylene glycol monoamine
    (PEO)3-mono-amine
  • Purity:
    ≥95%
  • MF:
    C6H15NO3
  • MW:
    149.18
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:

Monodisperse Amino-PEG3-alcohol (NH2-PEG3-OH) is a heterobifunctional PEG linker consisting of an amino (NH2) group and a hydroxyl group (OH). The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydroxyl group can be further converted to other functional group.

NH2-PEG3-OH is a PEG-based PROTAC linker used in the synthesis of the PROTAC (β-NF-JQ1).

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References:
​Ohoka N,et al. Development of Small Molecule Chimeras That Recruit AhR E3 Ligase to Target Proteins. ACS Chem Biol. 2019 Oct 16.