• CAS No.：
  1286281-32-0
• Synonyms：
  Amino-PEG6-t-butyl ester
  
• Purity：
  ≥95%
• MF：
  C₁₉H₃₉NO₈
• MW：
  409.5
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

NH2-PEG6-CH2CH2COOtBu (Amino-PEG6-t-butyl ester) is a PEG-based reagent containing an amino group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer enhances solubility in aqueous media, making it suitable for a variety of applications. The amino group is reactive with carboxylic acids, activated NHS esters, and carbonyl compounds (such as ketones and aldehydes), enabling efficient conjugation. The t-butyl protected carboxyl group can be deprotected under acidic conditions, allowing further functionalization.

This compound serves as a versatile PROTAC linker in PROTAC synthesis, and as a non-cleavable 6-unit PEG ADC linker for the development of antibody-drug conjugates (ADCs), supporting targeted therapy applications in drug delivery and cancer treatment.

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