• CAS No.：
  518044-32-1
• Synonyms：
  OH-PEG4-TBA
  Hydroxy-PEG4-t-butyl ester
  1-Hydroxy-3,6,9,12-tetraoxapentadecan-15-oic acid tert-butyl ester
  
• Purity：
  ≥95%
• MF：
  C₁₅H₃₀O₇
• MW：
  322.39
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

OH-PEG4-CH2CH2COOtBu (Hydroxy-PEG4-t-butyl ester) is a versatile PEG linker featuring a hydroxyl group and a t-butyl ester. The hydrophilic PEG spacer improves solubility in aqueous environments, making it suitable for diverse bioconjugation and synthesis applications. The hydroxyl group allows for further chemical modifications or replacement with other reactive functional groups, while the t-butyl-protected carboxyl group can be selectively deprotected under acidic conditions to expose a free carboxylic acid.

OH-PEG4-CH2CH2COOtBu  is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC. 

Biopharma PEG offers a wide range of PEG linkers on both lab and commercial scales. Email at sales@biochempeg.com and start using a superior product for your next product R&D project.