• Synonyms：
  Silane-PEG-Hydroxy
  
• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  

Silane-PEG-OH refers to a silane-based PEG chain terminated with a hydroxyl group. The silane group enables the attachment of the PEG chain to surfaces containing silanol groups (Si-OH), such as glass, silica, or other metal oxide surfaces, through siloxane bond formation. The PEG chain provides hydrophilicity and biocompatibility, while the hydroxyl group allows for further chemical modification or conjugation with various functional groups. 

Applications:
· ​Silicon and glass surface modification
· ​Biosensor interfaces
· ​Nanomaterial functionalization
· ​PEGylated surface coatings
· ​Biointerface and microfluidic research

Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. Bharath Kumar Yadlapalli, Tzu-Chen Huang, Yu-Hsiang Lee, Yu-Che Cheng, Wen-Yih Chen; Deferoxamine-B–Functionalized Silicon Nanowire Field-Effect Transistor Interfaces for Ultralow-Concentration Fe3+ Detection in Semiconductor Process Chemicals. ACS Appl. Mater. Interfaces 2026; https://doi.org/10.1021/acsami.6c05478
2. Bharath Kumar Yadlapalli, Pei-Jun Wu, Yu-Hsiang Lee, Wen-Yih Chen,Simultaneous detection of miR-21 and miR-155 using a multiplexed silicon nanowire FET biosensor, Microchemical Journal,Volume 224, 2026, 117657, ISSN 0026-265X, https://doi.org/10.1016/j.microc.2026.117657.
3. ​Chia-Hsuan Lee, Wen-Pin Hu, Wen-Yih Chen, Electric-field assisted silicon nanowire field effect transistor for the ultra-low concentration nucleic acid detection, Biosensors and Bioelectronics, Volume 268, 2025, 116909, ISSN 0956-5663, https://doi.org/10.1016/j.bios.2024.116909. 
4. Panuška, P., Smejkal, J., Štofik, M. et al. Advanced Microfluidic Platform for Tumor Spheroid Formation and Cultivation Fabricated from OSTE+ Polymer. BioChip J 18, 393–409 (2024). https://doi.org/10.1007/s13206-024-00167-x 
5. Wen-Pin Hu, Yong-Qi Yang, Chia-Hsuan Lee, Cao-An Vu, Wen-Yih Chen, Comparing solution-gate and bottom-gate nanowire field-effect transistors on pH sensing with different salt concentrations and surface modifications, Talanta, Volume 271, 2024, 125731, ISSN 0039-9140, https://doi.org/10.1016/j.talanta.2024.125731. 
6. Cao-An Vu, Yi-Ting Su, Jui-Shen Wang, Chia-Yu Chang, Wen-Pin Hu, Chun-Jen Huang, Hardy Wai-Hong Chan, Wen-Yih Chen, Comparing surface modification methods for silicon nanowire field-effect transistor biosensors for diagnosis applications: A case study of cardiac troponin I, Colloids and Surfaces A: Physicochemical and Engineering Aspects, Volume 676, Part A, 2023, 132146, ISSN 0927-7757, https://doi.org/10.1016/j.colsurfa.2023.132146. 
7. Lin, Y., Chen, W., Hwu, E., & Hu, W. (2021). In-Silico Selection of Aptamer Targeting SARS-CoV-2 Spike Protein. International Journal of Molecular Sciences, 23(10), 5810. https://doi.org/10.3390/ijms23105810 
8. Vu, C., Pan, P., Yang, Y., Chan, H. W., Kumada, Y., & Chen, W. (2020). Combination of Aptamer Amplifier and Antigen-Binding Fragment Probe as a Novel Strategy to Improve Detection Limit of Silicon Nanowire Field-Effect Transistor Immunosensors. Sensors, 21(2), 650. https://doi.org/10.3390/s21020650 
9. Vu, C., Chen, W., Yang, Y., & Chan, H. W. H. (2021). Improved biomarker quantification of silicon nanowire field-effect transistor immunosensors with signal enhancement by RNA aptamer: Amyloid beta as a case study. Sensors and Actuators B: Chemical, 329, 129150. https://doi.org/10.1016/j.snb.2020.129150

View more publications citing Biopharma PEG products.

Related Products & Categories

• ● Category: Silane PEGs | Hydroxyl(OH) PEG
• ● Silane Functional PEGs: Silane-PEG-NHS | Silane-PEG-NH2 | Silane-PEG-COOH | Silane-PEG-N3 | Silane-PEG-Biotin | mPEG-Silane