• Synonyms：
  Methoxy-PEG-Silane
  
• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-silane (Methoxy PEG Silane) is a linear monofunctional methyl ether PEG with a reactive tri-ethoxy silane group designed for glass/silica/metal surface modification and deactivation. Silane PEG is often used to PEGylate glass and hydroxylated surfaces and particles. Different MW of mPEG Silane products may be available by custom synthesis. 

Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. Wen, J.; Lei, C.; Hua, S.; Cai, L.R.Y.; Dai, H.; Liu, S.Y.; Li, Y.W.; Ivanovski, S.; Xu, C. Regulation of macrophage uptake through the bio-nano interaction using surface functionalized mesoporous silica nanoparticles with large radial pores. J. Mater. Chem. B 2024, 13, 137–150. https://doi.org/10.1039/D4TB01124D 
2. Daichi Nakajima, Nozomi Takahashi, Takanari Inoue, Shin-ichiro M. Nomura, Hideaki T. Matsubayashi,
   A unified purification method for actin-binding proteins using a TEV-cleavable His-Strep-tag, MethodsX, Volume 13, 2024, 102884, ISSN 2215-0161, https://doi.org/10.1016/j.mex.2024.102884. 
3. Wen H, Martínez MG, Happonen E, et al. A PEG-assisted membrane coating to prepare biomimetic mesoporous silicon for PET/CT imaging of triple-negative breast cancer. Int J Pharm. 2024;652:123764. doi:10.1016/j.ijpharm.2023.123764 
4. Wen, H.; Poutiainen, P.; Batnasan, E.; Latonen, L.; Lehto, V.-P.; Xu, W. Biomimetic Inorganic Nanovectors as Tumor-Targeting Theranostic Platform against Triple-Negative Breast Cancer. Pharmaceutics 2023, 15, 2507. https://doi.org/10.3390/pharmaceutics15102507 
5. Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy, Published in Volume 133, Issue 19 on October 2, 2023J Clin Invest. 2023;133(19):e171356. https://doi.org/10.1172/JCI171356. 
6. Sekine, R., Tsuno, S., Irokawa, H., Sumitomo, K., Han, T., Sato, Y., Nishizawa, S., Takeda, K., & Kuge, S. (2023). Inhibition of SARS-CoV-2 nucleocapsid protein–RNA interaction by guanosine oligomeric RNA. The Journal of Biochemistry, 173(6), 447-457. https://doi.org/10.1093/jb/mvad008 
7. Functionalized silica nanoplatform as a bimodal contrast agent for MRI and optical imaging, Nanoscale, 2021,13, 16509-16524, https://doi.org/10.1039/D1NR04972K
8. ​Wack, M., Wiegand, T., Frischknecht, F. and Cavalcanti-Adam, E. A. (2020). An in vitro DNA Sensor-based Assay to Measure Receptor-specific Adhesion Forces of Eukaryotic Cells and Pathogens. Bio-protocol 10(17): e3733. DOI: 10.21769/BioProtoc.3733. 
9. Lee, J., Choi, S. W., Park, M., Um, W., Kwon, S., Kim, C. H., Joo, H., You, D. G., Lee, J. A., Shin, S., Kang, H., Ghahari, F., Kim, J., & Park, J. H. (2025). Hematite-embedded mesoporous nanoparticles for ferroptosis-inducing cancer sonoimmunotherapy. Journal of Controlled Release, 113990. https://doi.org/10.1016/j.jconrel.2025.113990

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