• CAS No.：
  80506-64-5
• Synonyms：
  mPEG-Amine
  
• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-NH2 is a monofunctional PEG derivative with a reactive primary amine group (NH2) attached to the terminal site, which can quickly react with activated carboxylic acids such as NHS esters to form a stable amide bond.

In conjugation chemistry, the amine group of mPEG-NH2 provides a convenient reactive site for forming stable covalent bonds with target molecules. This makes it especially valuable in pharmaceutical development, where controlled modification and improved biological performance are often required.

Bulk supply and custom specifications of mPEG-NH2 are commonly available for research and production needs. Email us at [email protected] for more details. 

Cited Publications

Our mPEG-NH2 has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. Heewon Yoon, Yewon Keum, Jung-Eun Lee, Yoon-Jee Chae, Ji-Eun Chang, Improved tumor accumulation and photodynamic antitumor efficacy of a PEGylated photosensitizer, Journal of Photochemistry and Photobiology B: Biology, Volume 280, 2026, 113480, ISSN 1011-1344, https://doi.org/10.1016/j.jphotobiol.2026.113480.
2. Velay, M., & Comtet, J. (2026). Macromolecular tribology at flowing solid/liquid interfaces. ArXiv. https://arxiv.org/abs/2605.04318
3. Kirkpatrick, B. E., Dhand, A. P., Hibbard, L. P., Jaeschke, M. W., Yendamuri, T., Nelson, B. R., Lee, J. S., Bera, K., Zlotnick, H. M., Fox, C. A., Meurer-Zeman, B., Miksch, C. E., Skillin, N. P., Blatchley, M. R., White, T. J., Bowman, C. N., Burdick, J. A., & Anseth, K. S. (2025). Ultrafast-relaxing and photopolymerizable PEG hydrogels enable viscoelasticity-mediated cell remodeling in synthetic matrices. Matter, 102524. https://doi.org/10.1016/j.matt.2025.102524
4. Polyanion Chemistry Engineers Ternary RNA Nanoparticle Structure/Function from the Inside-Out, Lijun Hu, David J. Peeler, Tianyi Jin, James J. Doutch, Baihao Shao, Jonathan Yeow, Li Ma, Hanna M. G. Barriga, Jiaqing Tang, Xuan Cao, Chenchen Liu, Christopher L. Grigsby, Alfredo Alexander-Katz, Robin J. Shattock, and Molly M. Stevens, ACS Nano Article ASAP, DOI: 10.1021/acsnano.5c19683
5. Ultrasensitive quantitative protein detection using Eu-ion doped vanadate nanoparticles,  Robin Kuhner, Christophe Cardone, Rafael Vieira Perrella, Fanny Mousseau, Rabei Mohammedi, Jean-Marc Sintes, Christine Bourgeois, Olivier Lambotte, Thierry Gacoin, Cedric I. Bouzigues, Antigoni Alexandrou, bioRxiv 2025.06.03.657629; doi: https://doi.org/10.1101/2025.06.03.657629
6. So Hee Kim, Chan Ho Kim, Chang Hyun Lee, Jungmi Lee, Heegun Kang, Sohyun Cho, Won Ho Jang, Minsung Park, Minji Ha, Jiyeon Kim, Wooram Um, Seunglee Kwon, Sangho Lee, Jin Woong Kim, Chan-Hwa Chung, Jae Hyung Park, Glycoengineered stem cell-derived extracellular vesicles for targeted therapy of acute kidney injury, Biomaterials, Volume 318, 2025, 123165, ISSN 0142-9612, https://doi.org/10.1016/j.biomaterials.2025.123165. 
7. High-throughput antibody screening with high-quality factor nanophotonics and bioprinting, 2024, 2411.18557, arXiv, https://arxiv.org/abs/2411.18557 
8. K. Daoust, P.-L. Vallières, A. Tagnit-Hamou, J.P. Claverie,
   Carbon nanofibers encapsulated by polyethylene glycol increase the mechanical properties and durability of OPC mortars, Construction and Building Materials, Volume 447, 2024, 137986, ISSN 0950-0618, https://doi.org/10.1016/j.conbuildmat.2024.137986. 
9. Lu, Mengrou (2024). Developing Technological Platforms for Targeted Cancer Therapies, Protein Drug Delivery, and Pathogen Detection. Carnegie Mellon University. Thesis. https://doi.org/10.1184/R1/25797004.v1 
10. Shirasu, T., Yodsanit, N., Xie, X., Zhao, Y., Wang, Y., Xie, R., Huang, Y., Wang, B., Urabe, G., Gong, S., Guo, L., & Kent, K. C. (2021). An adventitial painting modality of local drug delivery to abate intimal hyperplasia. Biomaterials, 275, 120968. https://doi.org/10.1016/j.biomaterials.2021.120968 
11. Confeld, M. I., Mamnoon, B., Feng, L., Jensen-Smith, H., Ray, P., Froberg, J., Kim, J., Hollingsworth, M. A., Quadir, M., Choi, Y., & Mallik, S. (2020). Targeting the Tumor Core: Hypoxia-Responsive Nanoparticles for the Delivery of Chemotherapy to Pancreatic Tumors. Molecular pharmaceutics, 17(8), 2849–2863. https://doi.org/10.1021/acs.molpharmaceut.0c00247 

View more publications citing Biopharma PEG products.