Linear methoxy PEG (mPEG) derivatives are a PEG chain with a reactive group at one end, while the other end is capped with a methoxy group. There are many clinical and preclinical use of mPEG conjugates of proteins, peptides, aptamers, liposomes, red blood cells, viral vectors and other drug-delivery particles to improve the stability and the pharmaco-kinetic properties of drugs.

We provide mPEG derivatives with various functional groups from lab to GMP commercial scale, such as Amine (NH2), Thiol (SH), Azide (N3), NHS ester, Maleimide (Mal), Carboxylic Acid (COOH), AlKyne, Silane, Biotin, DBCO, DSPE, etc. You can find ideal mPEG for conjugation of the required quality with high levels of activation, narrow polydispersity and low diol content. mPEG derivatives not listed in our online catalog may be available by custom synthesis.

Reference:
Hutanu, D., et al., Recent Applications of Polyethylene Glycols (PEGs) and PEG Derivatives. Mod Chem appl, 2014, 2(132).