N3-PEG2-NH2
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MSDS
N3-PEG2-NH2

CatalogID: 10609 Purity: ≥95% CAS NO.: 166388-57-4

  • CAS No.:
    166388-57-4
  • Synonyms:
    Azido-PEG2-Amine
    2-[2-(2-Azidoethoxy)ethoxy]ethanamine
  • Purity:
    ≥95%
  • MF:
    C6H14N4O2
  • MW:
    174.2
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:
    Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Azido-PEG2-amine (N3-PEG2-NH2) is a bifunctional crosslinker containing an amino and an azide group. The amino group is reactive with carboxylic acids, activated NHS esters,. The azide(N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

It is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

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