• Synonyms：
  mPEG-Cholesterol
  
• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-Cholesterol, also known as mPEG-CLS, is a lipid-PEG conjugate that combines cholesterol with mPEG. This compound exhibits both hydrophilic and lipophilic properties, making it highly water-soluble. mPEG-Cholesterol is primarily used in the formulation of liposomes, where it enhances the stability and prolongs the circulation time of encapsulated drugs, thereby improving their delivery and therapeutic efficacy. Additionally, mPEG-Cholesterol is employed in the development of non-viral transfection reagents, aiding in the efficient and less toxic delivery of genetic material into cells.

Biopharma PEG offers a wide range of PEG products from lab to commercial scale. Email at sales@biochempeg.com and start using a superior product for your next product R&D project.

Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. ​PEGylated lipid screening, composition optimization, and structure–activity relationship determination for lipid nanoparticle-mediated mRNA deliver, https://doi.org/10.1039/D5NR00433K 
2. Kaizuka Y, Machida R. Antiviral Activity of Cell Membrane-Bound Amphiphilic Polymers. Langmuir. 2023;39(15):5408-5417. doi:10.1021/acs.langmuir.3c00054 
3. Barve, A., Jain, A., Liu, H., Zhao, Z., & Cheng, K. (2020). Enzyme-responsive polymeric micelles of cabazitaxel for prostate cancer targeted therapy. Acta Biomaterialia, 113, 501-511. https://doi.org/10.1016/j.actbio.2020.06.019

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