• Synonyms：
  4-ArmPEG-Thiol
  
• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

4-ArmPEG-SH is a multi-arm PEG derivative. Each end of the four arms of 4-Arm PEG-SH has a thiol group. The free thiol groups undergo selective reactions with maleimides, transition metals, and oxidants, making it an essential building block for reversible hydrogels, surface functionalization, issue engineering and drug delivery systems. PEG-SH in 4-ArmPEG-SH can be well oxidized by air to form disulfide bonds.

Cited Publications

The 4-ArmPEG-SH  has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. Pieters, A. (2026). Riboflavin : an endogenous photo-initiator for GelMA/PEG-SH hydrogels as scaffold for spinal cord injury treatment (T). University of British Columbia. Retrieved from https://open.library.ubc.ca/collections/ubctheses/24/items/1.0453276
2. Adaptive PEG Bis-dendron Hydrogels with Tunable Mechanics and Bioactivity, Evgeny Apartsin, Noël Richard, Birgit Habenstein, Antoine Loquet, Sophie Lecomte, and Marie-Christine Durrieu, Chemistry of Materials Article ASAP, DOI: 10.1021/acs.chemmater.6c00419
3. Zhang, Y., Wang, Q., Deng, W., Hazer, S., Luukkonen, A., Pranovich, A., H. Salo-Ahen, O. M., Österbacka, R., Xu, C., & Wang, X. “Grafting-to” Polymers of Xylan-g-allyl Glycidyl Ether Toughen PEG Hydrogel via Microphase Separation: Thermoresponsive and Photoreactive Molecular Assembly in DLP 3D Printing. Small, 2502129. https://doi.org/10.1002/smll.202502129
4. Chu, C.-W.; Cheng, W.-J.; Wen, B.-Y.; Liang, Y.-K.; Sheu, M.-T.; Chen, L.-C.; Lin, H.-L. Preparation and Rheological Evaluation of Thiol–Maleimide/Thiol–Thiol Double Self-Crosslinking Hyaluronic Acid-Based Hydrogels as Dermal Fillers for Aesthetic Medicine. Gels 2024, 10, 776. https://doi.org/10.3390/gels10120776 
5. Pranantyo, D., Yeo, C.K., Wu, Y. et al. Hydrogel dressings with intrinsic antibiofilm and antioxidative dual functionalities accelerate infected diabetic wound healing. Nat Commun 15, 954 (2024). https://doi.org/10.1038/s41467-024-44968-y

View more publications citing Biopharma PEG products.

Related Products & Categories

• ● Category: Multi-Arm PEG Derivatives | PEG Hydrogels
• ● Amine Hydrogel Crosslinkers: 4-Arm PEG-NH2 | 8-Arm PEG-NH2
• ● Multi-Arm NHS Esters: Y-shape-PEG-NHS |  4-Arm PEG-SG | 8-Arm PEG-SG | 4-Arm PEG-NHS
• ● Maleimide Crosslinking Partners: 4-Arm PEG-Mal | 8-Arm PEG-Mal
• ● 8-Arm Counterparts: 8-Arm PEG-SH