• Synonyms：
  Mal-PEG-AA
  Maleimide-PEG-Acetic Acid
  
• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Mal-PEG-COOH (Maleimide-PEG-Carboxylic Acid) is a linear heterobifunctional PEG reagent containing a thiol-reactive maleimide group at one end and an amine-reactive carboxylic acid group at the other. This dual-functional design enables precise, step-wise orthogonal conjugation between sulfhydryl (-SH) containing molecules and primary amines (-NH2) without risk of self-polymerization.

Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. Yuan, S., Yang, X., Bremmer, A. M., Wang, Y., Li, S., Chen, Y., You, Y., & Hu, Q. (2025). Programmable immunoprobiotics orchestrate antitumor immune response with Pin1 inhibition for pancreatic cancer treatment. Proceedings of the National Academy of Sciences, 122(34), e2507711122. https://doi.org/10.1073/pnas.2507711122

View more publications citing Biopharma PEG products.

Related Products & Categories

• ● Category: Bifunctional PEG Linkers | Maleimide(Mal) PEG |  Hydroxyl(OH) PEG
• ● Maleimide Linkers: Mal-PEG-NH2.HCl  | Mal-PEG-NHS | Mal-PEG-OH  | Mal-PEG-Mal 
• ● Carboxylic Acid (COOH) Linkers: SH-PEG-COOH | COOH-PEG-N3 | COOH-PEG-NH2.HCl
• ● Monofunctional PEGs: mPEG-MAL | mPEG-COOH