• CAS No.：
  99126-64-4
• Synonyms：
  mPEG-Maleimide
  
• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Methoxy polyethylene glycol maleimide (mPEG-MAL) is a linear monofunctional methyl ether PEG with a reactive maleimide group attached to the terminal site, which can selectively react with thiol group at pH 5-6 via a Michale addition reaction to form a stable C-S covalent bond.

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Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. In Vivo Comparison of Branched vs Linear Pegylation of a Capsule-Degrading Enzyme for Treatment of Anthrax, Jennifer Chua, Devina Mathur, Hannah Lankford, J. Matthew Meinig, Donald J. Chabot, Patricia M. Legler, and Arthur M. Friedlander, ACS Omega Article ASAP, DOI: 10.1021/acsomega.5c02119
2. Data-Independent Acquisition (DIA)-Based Label-Free Redox Proteomics (DIALRP) Reveals Novel Oxidative Stress Responsive Translation Factors, Daiki Kobayashi, Tomoyo Takami, Masaki Matsumoto,bioRxiv 2024.12.16.626735; doi: https://doi.org/10.1101/2024.12.16.626735 
3.  High-throughput single molecule microscopy with adaptable spatial resolution using exchangeable oligonucleotide labels
   Klarinda de Zwaan, Ran Huo, Myron N.F. Hensgens, Hannah Lena Wienecke, Miyase Tekpinar, Hylkje Geertsema, Kristin Grussmayer, bioRxiv 2024.10.30.621026; doi: https://doi.org/10.1101/2024.10.30.621026
4. Development of N-Terminally Modified Variants of the CXCR4-Antagonistic Peptide EPI-X4 for Enhanced Plasma Stability, Mirja Harms, Rikke Fabech Hansson, el., Journal of Medicinal Chemistry 2023 66 (22), 15189-15204​, DOI: 10.1021/acs.jmedchem.3c01128 
5. Engineering an Fc-Fusion of a Capsule Degrading Enzyme for the Treatment of Anthrax, Khushie Matharoo, Jennifer Chua, Junyoung R. Park, Susham Ingavale, Tanya M. Jelacic, Kayla M. Jurkouich, Jaimee R. Compton, J. Matthew Meinig, Donald Chabot, Arthur M. Friedlander, and Patricia M. Legler, ACS Infectious Diseases 2022 8 (10), 2133-2148, DOI: 10.1021/acsinfecdis.2c00227 
6. Park, H. H., Kim, H., Lee, H. S., Seo, E. U., Kim, J., Lee, J., Mun, Y., Yoo, S., An, J., Yun, M., Kang, N., Kim, D., Na, D. H., Hong, K. S., Jang, J. G., Ahn, J. H., Bae, J., Song, G. Y., Lee, J., . . . Lee, W. (2021). PEGylated nanoparticle albumin-bound steroidal ginsenoside derivatives ameliorate SARS-CoV-2-mediated hyper-inflammatory responses. Biomaterials, 273, 120827. https://doi.org/10.1016/j.biomaterials.2021.120827 
7. Kim, J., Kim, J. S., Min, K. H., Kim, Y., & Chen, X. (2021). Bombesin-Tethered Reactive Oxygen Species (ROS)-Responsive Nanoparticles for Monomethyl Auristatin F (MMAF) Delivery. Bioengineering, 8(4), 43. https://doi.org/10.3390/bioengineering8040043

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