Fmoc-NH-PEG12-COOH
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Fmoc-NH-PEG12-COOH

CatalogID: 11610 Purity: ≥95% CAS NO.: 756526-01-9

  • CAS No.:
    756526-01-9
  • Synonyms:
    1952360-91-6
    Fmoc-NH-PEG12-CH2CH2COOH
    O-(N-Fmoc-2-aminoethyl)-O'-(2-carboxyethyl)-undecathyleneglycol
    Fmoc-N-amido-PEG12-acid
    Fmoc-PEG12-propionic acid
  • Purity:
    ≥95%
  • MF:
    C42H65NO16
  • MW:
    839.963
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:

Fmoc-NH-PEG12-COOH, also known as Fmoc-N-amido-PEG12-acid,  is a PEG derivative containing a protected form of propionic acid modified with Fmoc (9-FLUORENYLME- THOXYCARBONYL) and PEG12 (polyethylene glycol 12). It is useful in the synthesis of peptides and biomolecules. For example, it can be used to tether peptides to proteins or other large biomolecules (e.g. nucleic acids). The attachment of hydrophobic peptides, NH2-PEG12, can effectively reduce aggregation. Also, it can act as a linker for Antibody-Drug Conjugates (ADCs)

Biopharma PEG offers a wide range of PEG products from lab to commercial scale in both non-GMP and GMP grades. Email at sales@biochempeg.com and start using a superior product for your next product R&D project.

References:
1. Fatty acid derivatives of dimeric inhibitors of PSD-95. / Strømgaard, Kristian (Inventor); Bach, Anders (Inventor); Nissen, Klaus Bertram (Inventor).
Patent No.: WO2015/078477A1. Jun 04, 2015.
​2. Masayasu Kuwahara, Miki Arimitsu, Masanori Sigeyasu, Masahiko Sisido, Synthesis of oxy-peptide nucleic acids with mixed sequences, Nucleic Acids Symposium Series, Volume 42, Issue 1, , Pages 31–32, https://doi.org/10.1093/nass/42.1.31