• CAS No.：
  756526-01-9
• Synonyms：
  1952360-91-6
  Fmoc-NH-PEG12-CH2CH2COOH
  O-(N-Fmoc-2-aminoethyl)-O'-(2-carboxyethyl)-undecathyleneglycol
  Fmoc-N-amido-PEG12-acid
  Fmoc-PEG12-propionic acid
  
• Purity：
  ≥95%
• MF：
  C₄₂H₆₅NO₁₆
• MW：
  839.963
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  

Fmoc-NH-PEG12-COOH, also known as Fmoc-N-amido-PEG12-acid,  is a PEG derivative containing a protected form of propionic acid modified with Fmoc (9-FLUORENYLME- THOXYCARBONYL) and PEG12 (polyethylene glycol 12). It is useful in the synthesis of peptides and biomolecules. For example, it can be used to tether peptides to proteins or other large biomolecules (e.g. nucleic acids). The attachment of hydrophobic peptides, NH2-PEG12, can effectively reduce aggregation. Also, it can act as a linker for Antibody-Drug Conjugates (ADCs)

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References:
1. Fatty acid derivatives of dimeric inhibitors of PSD-95. / Strømgaard, Kristian (Inventor); Bach, Anders (Inventor); Nissen, Klaus Bertram (Inventor).
Patent No.: WO2015/078477A1. Jun 04, 2015.
​2. Masayasu Kuwahara, Miki Arimitsu, Masanori Sigeyasu, Masahiko Sisido, Synthesis of oxy-peptide nucleic acids with mixed sequences, Nucleic Acids Symposium Series, Volume 42, Issue 1, , Pages 31–32, https://doi.org/10.1093/nass/42.1.31