Fmoc-NH-PEG2-COOH
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Fmoc-NH-PEG2-COOH

CatalogID: 10814 Purity: ≥95% CAS NO.: 872679-70-4

  • CAS No.:
    872679-70-4
  • Synonyms:
    Fmoc-NH-PEG2-CH2CH2COOH
    Fmoc-NH-PEG2-Propionic Acid
    Fmoc-9-Amino-4,7-Dioxanonanoic acid
    Fmoc-N-amido-PEG2-acid
  • Purity:
    ≥95%
  • MF:
    C22H25NO6
  • MW:
    399.44
  • Recommended Storage Condition:
    Store at -5°C,keep in dry and avoid sunlight.
  • Uses:
    Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Fmoc-NH-PEG2-COOH (CAS No.: 872679-70-4) is a versatile PEG linker featuring an Fmoc-protected amine and a terminal carboxylic acid. The Fmoc group can be removed under basic conditions to reveal a free amine, enabling further conjugation. The carboxylic acid group readily reacts with primary amines in the presence of activators like EDC or HATU to form stable amide bonds.

This linker serves as a cleavable ADC linker in the synthesis of antibody-drug conjugates (ADCs), facilitating precise payload delivery. Additionally, it functions as a PEG-based PROTAC linker, used in the development of PROTACs. 

Biopharma PEG offers a wide range of PEG linkers on both lab and commercial scales. Email at sales@biochempeg.com and start using a superior product for your next product R&D project.

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