• CAS No.：
  1403744-37-5
• Synonyms：
  DSPE-PEG-Acid
  DSPE-PEG-Carboxylic acid
  
• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

DSPE-PEG-COOH is a phospholipid PEG conjugate with hydrophilic and hydrophobic properties. DSPE-PEG-COOH is mostly used to prepare the surface of liposomes in practice. DSPE-PEG-COOH contains free-COOH long-circulating liposomes, which can be widely used in the delivery of targeted drugs and genes.

Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. ​Hee Won Park, Dae Hyun Lee, Sungjun Kim, Hyeri Park, Ashok Kumar Jangid, Chae Eun Lee, Jaewon Park, Gyu Tae Park, Ha Yeon Park, HyunJin Kim, Jae Ho Kim, Gi Jin Kim, Kyobum Kim, Amphiphilic Lipid-Peptide Engineered Placenta-Derived Mesenchymal Stem Cells for Liver Fibrosis Treatment, Asian Journal of Pharmaceutical Sciences, 2025, 101061, ISSN 1818-0876, https://doi.org/10.1016/j.ajps.2025.101061.
2. Bone Marrow-Targeted Liposomes Loaded with Bortezomib Overcome Multiple Myeloma Resistance, Rotem Menachem, Igor Nudelman, Avital Vorontsova, Ido Livneh, Mor Sela, Madeleine Benguigui, Bar Manobla, Yael Shammai, Abhilash Deo, Chen Buxbaum, Ron Bessler, Ziv Raviv, Jeny Shklover, Josué Sznitman, Aaron Ciechanover, Avi Schroeder, and Yuval Shaked, ACS Nano 2025 19 (12), 11684-11701, DOI: 10.1021/acsnano.4c10597 
3. Luo, C., Hsu, Y., Wu, W., Chang, K., & Yeh, C. (2021). Phage Digestion of a Bacterial Capsule Imparts Resistance to Two Antibiotic Agents. Microorganisms, 9(4), 794. https://doi.org/10.3390/microorganisms9040794 

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