• Purity：
  ≥95%
• Recommended Storage Condition：
  Store at -5°C,keep in dry and avoid sunlight.
• Uses：
  Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

DSPE-PEG-DSPE is a lipid-based PEG derivative terminated with two DSPE moieties. This compound is commonly used in the formulation of liposomes and lipid nanoparticles for drug delivery applications.

The DSPE lipids provide stability and integrity to lipid-based carriers, while the PEG spacer enhances circulation time and stealth properties by reducing opsonization and recognition by the immune system. DSPE-PEG-DSPE offers several advantages in drug delivery, including prolonged circulation half-life, improved biodistribution, and enhanced tumor accumulation via the enhanced permeability and retention (EPR) effect.

Biopharma PEG offers a wide range of PEG products from lab to commercial scale in both non-GMP and GMP grades. Email at sales@biochempeg.com and start using a superior product for your next product R&D project.

Cited Publications

This PEG derivative has been cited in peer-reviewed scientific publications. Browse the references below to learn more.

1. Lee J, Lee S, Lee H, Tran TTP, Kim BC, Rhee WJ. In Situ Simultaneous Detection of Surface Protein and microRNA in Clustered Extracellular Vesicles from Cancer Cell Lines Using Flow Cytometry. ACS Biomater Sci Eng. 2023;9(11):6369-6378. doi:10.1021/acsbiomaterials.3c01459 
2. Yang, H. C., & Rhee, W. J. (2020). Single Step In Situ Detection of Surface Protein and MicroRNA in Clustered Extracellular Vesicles Using Flow Cytometry. Journal of Clinical Medicine, 10(2), 319. https://doi.org/10.3390/jcm10020319

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